Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31224856 | 0.86 | MAPT (0.42) | BPTFBRD4SLC18A3LMNAGAA | |
| SCHEMBL16669158 | 0.83 | NOTUM (0.53) | SLC18A3NOTUMMAPTMBTD1L3MBTL3 | |
| SCHEMBL2725262 | 0.80 | FFAR4 (0.56) | SLC18A3NOTUMDRD2DRD4 | |
| SCHEMBL31224958 | 0.78 | MAPT (0.51) | ADRB1LMNAGAAMAPTL3MBTL1 | |
| SCHEMBL7446491 | 0.77 | MBTD1 (0.55) | SLC18A3SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL5537574 | 0.76 | BPTF (0.47) | BPTFSLC18A3SIGMAR1HTR3EHTR3B | |
| SCHEMBL11696584 | 0.76 | G6PD (0.47) | BPTFBRD4SLC18A3SIGMAR1GAA | |
| SCHEMBL23978897 | 0.73 | BRD4 (0.44) | BRD4SLC18A3SIGMAR1DRD2DRD4 | |
| SCHEMBL3121777 | 0.73 | BPTF (0.54) | BPTFSIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL2330436 | 0.73 | BPTF (0.54) | BPTFSIGMAR1HTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104703987-B | PDE9 inhibitors having an imidazopyrazinone backbone | H.隆德贝克有限公司 | 2017-05-03 | — | — | CN | claimed |