Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14699029 | 0.84 | CREBBP (0.55) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL14228185 | 0.81 | LMNA (0.63) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL21523770 | 0.81 | LMNA (0.58) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL2360147 | 0.81 | ALDH1A1 (0.60) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL1978804 | 0.80 | MEN1 (0.56) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL712395 | 0.78 | MEN1 (0.58) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL166869 | 0.78 | LMNA (0.55) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL3599147 | 0.78 | KMT2A (0.59) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL14200041 | 0.78 | ALDH1A1 (0.60) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL29276679 | 0.78 | MEN1 (0.55) | MEN1KMT2ALMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106687455-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2017-05-17 | — | — | CN | disclosed |