Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10430283 | 0.98 | MTNR1A (0.44) | MTNR1AMTNR1BPARP10POLBSRD5A2 | |
| SCHEMBL6062607 | 0.83 | HSP90AB1 (0.60) | MTNR1AMTNR1BPOLBNPC1HPGD | |
| SCHEMBL4213704 | 0.82 | POLB (0.57) | PARP10POLBSRD5A2AKR1C3HPGD | |
| SCHEMBL27811253 | 0.82 | MTNR1A (0.48) | MTNR1AMTNR1BPOLBSRD5A2AKR1C3 | |
| SCHEMBL27731757 | 0.81 | MAOB (0.58) | PARP10NPC1HPGDRAB9AMAOB | |
| SCHEMBL1633279 | 0.81 | MEN1 (0.49) | MTNR1AMTNR1BNPC1HPGDRAB9A | |
| SCHEMBL27491890 | 0.81 | PARP10 (0.58) | PARP10POLBAKR1C3MAOBMAOA | |
| Hydrochloric Acid SCHEMBL27535246 | 0.80 | MAOB (0.57) | PARP10NPC1HPGDRAB9AMAOB | |
| SCHEMBL4213887 | 0.80 | ALDH1A1 (0.57) | PARP10POLBAKR1C3HDAC3BRAF | |
| SCHEMBL14428212 | 0.80 | PARP10 (0.47) | PARP10POLBSRD5A2AKR1C3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106588806-A | Bromophenol-oxazole compound and its use in drug for treatment on diabetes mellitus type 2 | 中国科学院海洋研究所 | 2017-04-26 | — | — | CN | disclosed |