SCHEMBL28138985

SCHEMBL28138985

FC(F)(F)Oc1ccccc1.FC(F)(F)Sc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
PTPRZ1 P23471 3/20 0.42
PTPN1 P18031 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KCNK2 O95069 2/20 0.42
KCNK10 P57789 2/20 0.42
KIF11 P52732 2/20 0.41
GRIN2B Q13224 1/20 0.37
EPHX1 P07099 1/20 0.36
MAPT P10636 2/20 0.36
SLC7A5 Q01650 2/20 0.36
CCR6 P51684 1/20 0.36
KCNH2 Q12809 1/20 0.36
ATM Q13315 1/20 0.36
PLA2G1B P04054 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
CETP P11597 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777056 0.82 ALDH1A1 (0.56) LMNAPTPRZ1PTPN1KDM4EALDH1A1
SCHEMBL168125 0.82 KIF11 (0.47) KIF11GRIN2BMAPTSLC7A5CCR6
Ammonia Solution, Strong SCHEMBL2163079 0.80 KIF11 (0.46) KIF11GRIN2BMAPTSLC7A5CCR6
SCHEMBL4036806 0.80 KIF11 (0.46) KIF11GRIN2BMAPTSLC7A5CCR6
Water SCHEMBL28356277 0.80 ALDH1A1 (0.54) LMNAPTPRZ1PTPN1KDM4EALDH1A1
Fluoride SCHEMBL28371495 0.80 KIF11 (0.46) KIF11GRIN2BMAPTSLC7A5CCR6
SCHEMBL29087324 0.80 KIF11 (0.46) KIF11GRIN2BMAPTSLC7A5CCR6
SCHEMBL4036809 0.80 KIF11 (0.46) KIF11GRIN2BMAPTSLC7A5CCR6
Ethyne SCHEMBL28472442 0.78 KIF11 (0.44) KIF11GRIN2BMAPTSLC7A5CCR6
Nitrogen SCHEMBL29122681 0.78 KIF11 (0.44) KIF11GRIN2BMAPTSLC7A5CCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106609137-A Dark blue organic light-emitting material and preparation method and application thereof 北京大学深圳研究生院 2017-05-03 CN claimed
CN-106609137-A Dark blue organic light-emitting material and preparation method and application thereof 北京大学深圳研究生院 2017-05-03 CN disclosed