SCHEMBL28138993

SCHEMBL28138993

CCCCCCn1c2ccccc2c2cccc(O)c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
MAPT P10636 1/20 0.53
ALDH1A1 P00352 2/20 0.52
CNR2 P34972 6/20 0.52
CNR1 P21554 3/20 0.52
PSEN1 P49768 5/20 0.51
PSEN2 P49810 5/20 0.51
APH1B Q8WW43 5/20 0.51
NCSTN Q92542 5/20 0.51
APH1A Q96BI3 5/20 0.51
PSENEN Q9NZ42 5/20 0.51
HTT P42858 3/20 0.50
SLC6A3 Q01959 1/20 0.50
PGR P06401 1/20 0.50
RORA P35398 1/20 0.50
RORC P51449 1/20 0.50
RORB Q92753 1/20 0.50
TLR8 Q9NR97 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ALPL P05186 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28138954 0.99 KDM4E (0.55) KDM4EMAPTALDH1A1CNR2CNR1
Benzene SCHEMBL28138961 0.99 KDM4E (0.55) KDM4EMAPTALDH1A1CNR2CNR1
Benzene SCHEMBL28139603 0.99 KDM4E (0.55) KDM4EMAPTALDH1A1CNR2CNR1
SCHEMBL17775032 0.86 PGR (0.57) KDM4EMAPTALDH1A1CNR2PSEN1
SCHEMBL17775036 0.86 PGR (0.57) KDM4EMAPTALDH1A1CNR2PSEN1
SCHEMBL17775031 0.86 PGR (0.57) KDM4EMAPTALDH1A1CNR2PSEN1
SCHEMBL15667726 0.84 PGR (0.58) KDM4EMAPTALDH1A1CNR2PSEN1
SCHEMBL28374675 0.84 PSEN1 (0.55) KDM4EMAPTALDH1A1CNR2CNR1
SCHEMBL28369297 0.84 PSEN1 (0.55) KDM4EMAPTALDH1A1CNR2CNR1
SCHEMBL28369488 0.84 PSEN1 (0.55) KDM4EMAPTALDH1A1CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106674514-B A kind of polyarylether, preparation method and nano-carbon modified material and composite material of the main chain containing carbazole 吉林大学 2018-10-23 CN disclosed
CN-106674514-A Polyarylether with main chain containing carbazole, preparation method, nanocarbon modified material and composite 吉林大学 2017-05-17 CN disclosed