Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | RORA | P35398 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | RORB | Q92753 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 8/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28374675 | 1.00 | PSEN1 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28369297 | 1.00 | PSEN1 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28767719 | 0.88 | ALDH1A1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17775036 | 0.85 | PGR (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17775032 | 0.85 | PGR (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17775031 | 0.85 | PGR (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28138993 | 0.84 | KDM4E (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15667726 | 0.83 | PGR (0.58) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Benzene SCHEMBL28138961 | 0.83 | KDM4E (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Benzene SCHEMBL28138954 | 0.83 | KDM4E (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110759852-A | Preparation method of 3-hydroxymethyl-9-substituted carbazole | 陕西科技大学 | 2020-02-07 | — | — | CN | disclosed |