Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16975511 | 0.81 | MAPT (0.39) | KLKB1L3MBTL1SCDPIK3CDPKM | |
| SCHEMBL28104942 | 0.78 | RAB9A (0.44) | KLKB1TPMTL3MBTL1PKMMAPK1 | |
| SCHEMBL28139274 | 0.75 | HSD17B10 (0.51) | KLKB1TPMTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28139265 | 0.73 | KLKB1 (0.53) | KLKB1L3MBTL1 | |
| SCHEMBL23762953 | 0.72 | CRHR1 (0.37) | L3MBTL1SCDCRHR1ALDH1A1 | |
| SCHEMBL14764016 | 0.70 | SCD (0.43) | KLKB1L3MBTL1SCDPIK3CDPKM | |
| SCHEMBL28104875 | 0.69 | KDM5A (0.44) | TPMTALDH1A1 | |
| SCHEMBL29910512 | 0.68 | L3MBTL1 (0.56) | KLKB1L3MBTL1PIK3CDENPP2KDM1A | |
| SCHEMBL3259744 | 0.67 | PIK3CD (0.46) | KLKB1L3MBTL1PIK3CDENPP2PKM | |
| SCHEMBL28188377 | 0.67 | ENPP2 (0.40) | KLKB1PIK3CDENPP2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105940004-A | Compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2016-09-14 | — | — | CN | disclosed |