Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278531 | 0.97 | TSHR (0.37) | HCAR2TSHRHPGDDNM1TLR2 | |
| SCHEMBL9480754 | 0.82 | TSHR (0.40) | HCAR2TSHRHPGDDNM1PLA2G2C | |
| Pregabalin SCHEMBL27230104 | 0.82 | CACNA2D1 (0.49) | DNM1MMP9MMP8MMP13 | |
| SCHEMBL6274690 | 0.81 | TSHR (0.49) | HCAR2TSHRHPGDALDH1A1CNR1 | |
| Urea SCHEMBL28950349 | 0.80 | TSHR (0.46) | HCAR2TSHRHPGDDNM1LMNA | |
| SCHEMBL6272793 | 0.78 | TSHR (0.51) | HCAR2TSHRHPGDPLA2G2CALDH1A1 | |
| SCHEMBL11010126 | 0.75 | DNM1 (0.47) | TSHRDNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL27829562 | 0.75 | HCAR2 (0.36) | HCAR2TSHRHPGDPLA2G2C | |
| SCHEMBL2398433 | 0.74 | DNM1 (0.41) | TSHRHPGDDNM1ALDH1A1CNR1 | |
| SCHEMBL5820402 | 0.73 | TSHR (0.45) | HCAR2TSHRHPGDPLA2G2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107487-A2 | LIPID-DRUG CONJUGATES FOR DRUG DELIVERY | WU NIAN (US) | 2010-09-23 | — | — | WO | disclosed |