Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272793 | 0.85 | TSHR (0.51) | TSHRALDH1A1CES2HPGDPLA2G2C | |
| SCHEMBL278531 | 0.85 | TSHR (0.37) | TSHRALDH1A1CES2HPGDPLA2G2C | |
| SCHEMBL6274690 | 0.85 | TSHR (0.49) | TSHRALDH1A1HPGDNAAAHCAR2 | |
| Carbamic Acid SCHEMBL2813938 | 0.82 | HCAR2 (0.36) | TSHRALDH1A1HPGDPLA2G2CHCAR2 | |
| SCHEMBL5820402 | 0.80 | TSHR (0.45) | TSHRALDH1A1HPGDPLA2G2CHCAR2 | |
| SCHEMBL11010126 | 0.79 | DNM1 (0.47) | TSHRALDH1A1CNR1CNR2DNM1 | |
| SCHEMBL27829562 | 0.79 | HCAR2 (0.36) | TSHRHPGDPLA2G2CNAAAHCAR2 | |
| SCHEMBL2398433 | 0.77 | DNM1 (0.41) | TSHRALDH1A1HPGDCNR1CNR2 | |
| SCHEMBL27220525 | 0.77 | TDP1 (0.39) | TSHRALDH1A1 | |
| Urea SCHEMBL28950349 | 0.77 | TSHR (0.46) | TSHRALDH1A1HPGDHCAR2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5103691-A | — | — | None | — | — | JP | disclosed |
| JP-5103693-A | — | — | None | — | — | JP | disclosed |
| JP-5103692-A | — | — | None | — | — | JP | disclosed |
| JP-H05103691-A | PRODUCTION OF OPTICALLY ACTIVE ALCOHOL | MITSUBISHI KASEI CORP | 1993-04-27 | — | — | JP | disclosed |
| JP-H05103693-A | PRODUCTION OF OPTICALLY ACTIVE ALCOHOL | MITSUBISHI KASEI CORP | 1993-04-27 | — | — | JP | disclosed |
| JP-H05103692-A | PRODUCTION OF OPTICALLY ACTIVE ESTER | MITSUBISHI KASEI CORP | 1993-04-27 | — | — | JP | disclosed |
| EP-0532511-A1 | TRETRA-SUBSTITUTED METHANES WITH LIQUID CRYSTAL PROPERTIES. | CONSORTIUM ELEKTROCHEM IND (DE) | 1993-03-24 | — | — | EP | disclosed |