Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.52 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 7/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL28101723 | 0.98 | STK17B (0.50) | STK17BSTK17AMTNR1AMTNR1BCKS1B | |
| SCHEMBL24110648 | 0.83 | MTNR1A (0.46) | STK17BSTK17AMTNR1AMTNR1BCKS1B | |
| SCHEMBL31637422 | 0.81 | BRD4 (0.44) | STK17BSTK17AMTNR1AMTNR1BDRD2 | |
| SCHEMBL27156693 | 0.81 | STK17B (0.53) | STK17BSTK17ACKS1BSKP1SKP2 | |
| SCHEMBL28953978 | 0.80 | STK17B (0.47) | STK17BSTK17ACKS1BSKP1SKP2 | |
| SCHEMBL21268786 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BCKS1BSKP1SKP2 | |
| SCHEMBL28175138 | 0.78 | STK17B (0.44) | STK17BSTK17ACKS1BSKP1SKP2 | |
| SCHEMBL24110645 | 0.78 | MTNR1A (0.47) | MTNR1AMTNR1BDRD2BRD4 | |
| SCHEMBL24669199 | 0.77 | DRD2 (0.43) | STK17BSTK17AMTNR1ADRD2 | |
| SCHEMBL29437373 | 0.77 | STK17B (0.49) | STK17BSTK17ACKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936745-B | Cdk inhibitors | G1治疗公司 | 2017-04-12 | — | — | CN | disclosed |