Benzene

Benzene

SCHEMBL28139802

Brc1ccc2[nH]ccc2c1.CC.c1ccccc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.84
NR4A2 P43354 2/20 0.84
CYP2A6 P11509 2/20 0.84
NPC1 O15118 2/20 0.53
MAOA P21397 2/20 0.49
MAOB P27338 2/20 0.49
F7 P08709 1/20 0.48
LTA4H P09960 1/20 0.48
F3 P13726 1/20 0.48
USP2 O75604 1/20 0.48
GAA P10253 1/20 0.48
ALOX15 P16050 1/20 0.48
RAD51 Q06609 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
TRPA1 O75762 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ITGB2 P05107 1/20 0.45
ICAM1 P05362 1/20 0.45
ITGAL P20701 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL27630420 0.96 AHR (0.91) AHRNR4A2CYP2A6NPC1MAOA
SCHEMBL74304 0.92 AHR (1.00) AHRNR4A2CYP2A6NPC1MAOA
Methane SCHEMBL27911670 0.90 AHR (0.95) AHRNR4A2CYP2A6NPC1MAOA
SCHEMBL27718483 0.90 AHR (0.95) AHRNR4A2CYP2A6NPC1MAOA
SCHEMBL27701610 0.90 AHR (0.95) AHRNR4A2CYP2A6NPC1MAOA
Toluene SCHEMBL28036262 0.89 AHR (0.72) AHRNR4A2CYP2A6NPC1MAOA
Biphenyl SCHEMBL28811949 0.89 AHR (0.78) AHRNR4A2CYP2A6NPC1MAOA
Acetic Acid SCHEMBL27942661 0.87 AHR (0.75) AHRNR4A2CYP2A6NPC1MAOA
Indole SCHEMBL28308910 0.86 AHR (0.81) AHRNR4A2CYP2A6NPC1MAOA
Cyanide SCHEMBL31107451 0.86 AHR (0.88) AHRNR4A2CYP2A6NPC1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105130723-B Bisindole methane derivative promotes the method that CuCl is catalyzed Sonogashira cross-coupling reactions 陕西师范大学 2017-04-05 CN disclosed