SCHEMBL74304

SCHEMBL74304

Brc1ccc2[nH]ccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 1.00
NR4A2 P43354 2/20 1.00
CYP2A6 P11509 2/20 1.00
F7 P08709 1/20 0.56
LTA4H P09960 1/20 0.56
F3 P13726 1/20 0.56
USP2 O75604 1/20 0.56
GAA P10253 1/20 0.56
ALOX15 P16050 1/20 0.56
RAD51 Q06609 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
MAOA P21397 1/20 0.54
MAOB P27338 1/20 0.54
CSNK2A1 P68400 2/20 0.50
IMPDH2 P12268 1/20 0.50
IMPDH1 P20839 1/20 0.50
NPC1 O15118 1/20 0.50
PIM3 Q86V86 1/20 0.49
F2 P00734 1/20 0.47
NOS1 P29475 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL27911670 0.98 AHR (0.95) AHRNR4A2CYP2A6F7LTA4H
SCHEMBL27718483 0.98 AHR (0.95) AHRNR4A2CYP2A6F7LTA4H
SCHEMBL27701610 0.98 AHR (0.95) AHRNR4A2CYP2A6F7LTA4H
Ethane SCHEMBL27630420 0.96 AHR (0.91) AHRNR4A2CYP2A6F7LTA4H
Cyanide SCHEMBL31107451 0.94 AHR (0.88) AHRNR4A2CYP2A6F7LTA4H
Formaldehyde SCHEMBL28094648 0.94 AHR (0.88) AHRNR4A2CYP2A6F7LTA4H
SCHEMBL28197247 0.92 AHR (0.84) AHRNR4A2CYP2A6F7LTA4H
Benzene SCHEMBL28139802 0.92 AHR (0.84) AHRNR4A2CYP2A6F7LTA4H
Indole SCHEMBL28308910 0.90 AHR (0.81) AHRNR4A2CYP2A6F7LTA4H
Biphenyl SCHEMBL28811949 0.88 AHR (0.78) AHRNR4A2CYP2A6F7LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3762 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132380-A1 Hepatocyte Expansion Methods KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) 2026-05-14 US claimed
US-20260109670-A1 METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE Shanghai OuChem Bio-Technology Co., LTD (CN) 2026-04-23 US claimed
US-12497596-B2 Hepatocyte expansion methods KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) 2025-12-16 US claimed
CN-119980322-A Cu-Ni-based bimetallic catalytic system and electrochemical CO2Activated 5-bromoindole-2-carboxylic acid synthesis method 常州琦诺生物科技有限公司 2025-05-13 CN claimed
CN-119857098-A Application of indole triazole derivative in preparation of drug-resistant candida albicans drug 云南中医药大学 2025-04-22 CN claimed
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 EP claimed
CN-119490952-A In vitro induction of blastocysts and uses thereof 广州国家实验室 2025-02-21 CN claimed
WO-2025035461-A1 IN-VITRO BLASTOID INDUCTION AND USE OF BLASTOID 广州国家实验室 2025-02-20 WO claimed
CN-119425756-A Nitrogen-doped carbon-supported bimetallic catalyst as well as preparation method and application thereof 河南科技大学 2025-02-14 CN claimed
CN-119285641-A Tryptamine compound and preparation method and application thereof 昆明医科大学 2025-01-10 CN claimed
EP-1517931-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION Univation Technologies, LLC (US) 2005-03-30 EP claimed
EP-1517932-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION Univation Technologies LLC (US) 2005-03-30 EP claimed
EP-0729455-B1 INDOLE-DERIVED AZYLPIPERAZINES AS LIGANDS FOR 5HT1-LIKE RECEPTORS 5HT1B AND 5HT1D PF MEDICAMENT (FR) 2004-09-08 EP claimed
US-20040127348-A1 Halogen substituted catalyst system for olefin polymerization UNIVATION TECHNOLOGIES, LLC 2004-07-01 US claimed
WO-2004003037-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC. (US) 2004-01-08 WO claimed
WO-2004003032-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2004-01-08 WO claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed
US-4966977-A PEROXIDATION OF INDOLE COMPOUND MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-10-30 US claimed
US-4360594-A REACTING INDOLE COMPOUND WITH SERINE, OR WITH PYRUVIC ACID AND AMMONIUM ION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-11-23 US claimed
US-4349627-A Process for producing L-tryptophan or derivatives thereof using a microorganism ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-09-14 US claimed