Cyanide

Cyanide

SCHEMBL31107451

Brc1ccc2[nH]ccc2c1.C#N

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.88
NR4A2 P43354 2/20 0.88
CYP2A6 P11509 2/20 0.88
F7 P08709 1/20 0.50
LTA4H P09960 1/20 0.50
F3 P13726 1/20 0.50
IMPDH2 P12268 1/20 0.50
IMPDH1 P20839 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
USP2 O75604 1/20 0.50
GAA P10253 1/20 0.50
ALOX15 P16050 1/20 0.50
RAD51 Q06609 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
CSNK2A1 P68400 2/20 0.46
NPC1 O15118 1/20 0.46
PIM3 Q86V86 1/20 0.45
F2 P00734 1/20 0.43
NOS1 P29475 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74304 0.94 AHR (1.00) AHRNR4A2CYP2A6F7LTA4H
SCHEMBL27701610 0.91 AHR (0.95) AHRNR4A2CYP2A6F7LTA4H
SCHEMBL27718483 0.91 AHR (0.95) AHRNR4A2CYP2A6F7LTA4H
Methane SCHEMBL27911670 0.91 AHR (0.95) AHRNR4A2CYP2A6F7LTA4H
Ethane SCHEMBL27630420 0.89 AHR (0.91) AHRNR4A2CYP2A6F7LTA4H
Formaldehyde SCHEMBL28094648 0.88 AHR (0.88) AHRNR4A2CYP2A6F7LTA4H
Benzene SCHEMBL28139802 0.86 AHR (0.84) AHRNR4A2CYP2A6F7LTA4H
SCHEMBL28197247 0.86 AHR (0.84) AHRNR4A2CYP2A6F7LTA4H
Indole SCHEMBL28308910 0.84 AHR (0.81) AHRNR4A2CYP2A6F7LTA4H
Pyrimidine SCHEMBL10956176 0.83 AHR (0.72) AHRNR4A2CYP2A6F7LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118440081-A Four-ring condensed skeleton compound containing indoline unit and synthesis method thereof 西南交通大学 2024-08-06 CN claimed
CN-118440081-A Four-ring condensed skeleton compound containing indoline unit and synthesis method thereof 西南交通大学 2024-08-06 CN disclosed