⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28907425 | 0.97 | TP53 (0.39) | — | |
| SCHEMBL537308 | 0.92 | TP53 (0.39) | — | |
| SCHEMBL536784 | 0.89 | TP53 (0.37) | — | |
| SCHEMBL2818039 | 0.89 | TP53 (0.37) | — | |
| SCHEMBL536275 | 0.81 | — | — | |
| SCHEMBL691481 | 0.81 | TP53 (0.48) | — | |
| SCHEMBL20465806 | 0.81 | TP53 (0.48) | — | |
| Hydrochloric Acid SCHEMBL6154472 | 0.79 | — | — | |
| SCHEMBL27458343 | 0.78 | TP53 (0.46) | — | |
| SCHEMBL27910344 | 0.73 | TP53 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354616-B | Diaryl-1, 2, 4-triazole compound and preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-26 | — | — | CN | disclosed |
| CN-117285512-A | 2, 5-diketopiperazine-imidazole compound, preparation method and application thereof | 大连万众益生大健康有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-113354616-A | Diaryl-1, 2, 4-triazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2021-09-07 | — | — | CN | disclosed |
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-109153650-A | Amine-substituted aryl or heteroaryl compounds as EHMT1 and EHMT2 inhibitors | EPIZYME股份有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-106117217-B | A kind of preparation method of fluozirconate | 南京远淑医药科技有限公司 | 2018-07-10 | — | — | CN | disclosed |
| EP-2414432-B1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | CHEVRON ORONITE CO (US) | 2017-05-31 | — | — | EP | disclosed |
| EP-3099685-A1 | NOVEL DIHYDROQUINOLIZINONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2016-12-07 | — | — | EP | disclosed |
| CN-106117217-A | A kind of preparation method of fluozirconate | 南京远淑医药科技有限公司 | 2016-11-16 | — | — | CN | disclosed |
| US-9315595-B2 | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | CHEVRON ORONITE COMPANY LLC (US) | 2016-04-19 | — | — | US | disclosed |
| WO-2015113990-A1 | NOVEL DIHYDROQUINOLIZINONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2015-08-06 | — | — | WO | disclosed |
| CN-102356114-B | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | CHEVRON ORONITE CO | 2014-06-25 | — | — | CN | disclosed |
| US-20140031497-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2014-01-30 | — | — | US | disclosed |
| US-8552122-B2 | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2013-10-08 | — | — | US | disclosed |
| CN-102356114-A | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | CHEVRON ORONITE CO | 2012-02-15 | — | — | CN | disclosed |
| US-20100249001-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2010-09-30 | — | — | US | disclosed |
| EP-2012791-A2 | 7,9-DIHYDRO-PURIN-8-ONE AND RELATED ANALOGS AS HSP90-INHIBITORS | Conforma Therapeutics Corporation (US) | 2009-01-14 | — | — | EP | disclosed |
| US-20070253896-A1 | 7,9-Dihydro-Purin-8-One and Related Analogs as HSP90-Inhibitors | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-11-01 | — | — | US | disclosed |
| WO-2007092496-A2 | 7,9-DIHYDRO-PURIN-8-ONE AND RELATED ANALOGS AS HSP90-INHIBITORS | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-08-16 | — | — | WO | disclosed |