SCHEMBL28142011

SCHEMBL28142011

CC(C)Sc1cc[c]cc1F

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNQ3 O43525 1/20 0.30
KCNQ2 O43526 1/20 0.30
KCNE1 P15382 1/20 0.30
KCNQ1 P51787 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161769 0.77
SCHEMBL4612965 0.73 ALDH1A2 (0.33) KCNE1
SCHEMBL7770272 0.72
SCHEMBL19361748 0.70 POLB (0.39) KCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL900438 0.69 PDE2A (0.34)
SCHEMBL1028713 0.68 FAAH (0.30)
SCHEMBL161731 0.66
SCHEMBL1231007 0.65 PDE2A (0.31)
SCHEMBL16055953 0.65 PDE2A (0.43)
SCHEMBL57893 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105263969-B Using metallocene polymerization catalyst preparation polyolefin and the method for copolymer 埃克森美孚化学专利公司 2017-04-05 CN claimed