Phosphine

Phosphine

SCHEMBL28142196

Cc1c[nH]c(-c2ccccc2)n1.P

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.50
MAPT P10636 1/20 0.50
HPGDS O60760 1/20 0.41
MTOR P42345 1/20 0.41
ADK P55263 1/20 0.41
NISCH Q9Y2I1 1/20 0.41
NR1H2 P55055 2/20 0.41
NR1H3 Q13133 2/20 0.41
POLB P06746 2/20 0.41
PIN1 Q13526 1/20 0.41
DCUN1D1 Q96GG9 3/20 0.39
KDM4E B2RXH2 4/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49612 0.98 GAA (0.52) GAAMAPTHPGDSMTORADK
SCHEMBL28329121 0.92 GAA (0.47) GAAMAPTHPGDSMTORADK
Pyrrole SCHEMBL28207656 0.89 MAPT (0.45) GAAMAPTHPGDSMTORADK
Pyridine SCHEMBL28941369 0.89 GAA (0.45) GAAMAPTHPGDSMTORADK
SCHEMBL28201939 0.87 GAA (0.44) GAAMAPTHPGDSMTORADK
Carbamic Acid SCHEMBL29249439 0.87 MAPT (0.47) GAAMAPTPOLBPIN1KDM4E
SCHEMBL27985279 0.87 MAPK1 (0.40) GAAMAPTHPGDSNISCHNR1H2
Octane SCHEMBL28114785 0.86 GAA (0.42) GAAMAPTNR1H3
2-Phenylimidazole SCHEMBL16347705 0.84 NISCH (0.68) GAAMAPTHPGDSMTORADK
SCHEMBL1264137 0.82 DCUN1D1 (0.47) GAAMAPTHPGDSNISCHDCUN1D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103946263-B insulating material using epoxy resin composition 爱沃特株式会社 2017-04-26 CN disclosed