SCHEMBL27985279

SCHEMBL27985279

Cc1c[nH]c(-c2ccc(-c3nc(C)c[nH]3)cc2)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.40
NISCH Q9Y2I1 1/20 0.39
GAA P10253 3/20 0.38
MAPT P10636 2/20 0.38
DCUN1D1 Q96GG9 1/20 0.35
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
PKM P14618 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
GFER P55789 1/20 0.32
TDO2 P48775 1/20 0.32
HPGDS O60760 1/20 0.31
TYMP P19971 1/20 0.31
MGAM O43451 2/20 0.31
SI P14410 2/20 0.31
MGAM2 Q2M2H8 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6647087 0.93 NISCH (0.48) MAPK1NISCHGAAMAPTDCUN1D1
SCHEMBL13680573 0.89 MAPK1 (0.54) MAPK1GAAMAPTDCUN1D1NPC1
SCHEMBL10554989 0.89 GAA (0.44) GAAMAPTNPC1RAB9APKM
SCHEMBL797826 0.89 TNKS (0.40) MAPK1GAAMAPTNPC1RAB9A
SCHEMBL3635215 0.89 NPC1 (0.44) MAPK1GAAMAPTNPC1RAB9A
SCHEMBL28279252 0.89 ALDH1A1 (0.46) GAAMAPTNPC1RAB9APKM
SCHEMBL49612 0.89 GAA (0.52) NISCHGAAMAPTDCUN1D1NPC1
Phosphine SCHEMBL28142196 0.87 GAA (0.50) NISCHGAAMAPTDCUN1D1NPC1
SCHEMBL10553981 0.86 KDM4E (0.50) GAANPC1RAB9APKMALDH1A1
SCHEMBL15293725 0.84 KDM4E (0.49) GAANPC1RAB9APKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104031076-B A kind of two imidazoles nitrogen ligand regulation and control 1,3,5-trimesic acid Zn complex and preparation method thereof HENGYANG NORMAL UNIVERSITY (CN) 2016-01-06 CN claimed
CN-104031076-A Diimidazole nitrogen ligand-controlled 1,3,5-trimesic acid zinc complex and preparation method thereof UNIV HENGYANG NORMAL 2014-09-10 CN claimed
CN-104031076-B A kind of two imidazoles nitrogen ligand regulation and control 1,3,5-trimesic acid Zn complex and preparation method thereof HENGYANG NORMAL UNIVERSITY (CN) 2016-01-06 CN disclosed
CN-104031076-A Diimidazole nitrogen ligand-controlled 1,3,5-trimesic acid zinc complex and preparation method thereof UNIV HENGYANG NORMAL 2014-09-10 CN disclosed
CN-104031076-A Diimidazole nitrogen ligand-controlled 1,3,5-trimesic acid zinc complex and preparation method thereof UNIV HENGYANG NORMAL 2014-09-10 CN disclosed