SCHEMBL28143403

SCHEMBL28143403

NC1(N)C=CC=CC1CCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.38
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
MAOA P21397 3/20 0.37
MAOB P27338 3/20 0.37
KDM1A O60341 2/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
CASP1 P29466 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28381016 0.76 CPA1 (0.33) TAAR1SMN1; SMN2ALDH1A1
SCHEMBL7883172 0.76 SLC18A2 (0.33)
SCHEMBL27602329 0.74 KDM4E (0.37) ALDH1A1
SCHEMBL31279437 0.70 SLC18A2 (0.35)
SCHEMBL30232911 0.69 FUCA1 (0.38) TAAR1SMN1; SMN2MAOBSLC6A3
SCHEMBL27437866 0.69 ALDH1A1 (0.42) TAAR1CYP2A6HTR2ASMN1; SMN2LOXL2
SCHEMBL734440 0.67 KDM1A (0.38) HTR2AMAOAMAOBKDM1A
SCHEMBL28240964 0.67 SLC18A2 (0.37) TAAR1SMN1; SMN2MAOAMAOBALDH1A1
SCHEMBL27275720 0.66 ALDH1A1 (0.39) TAAR1CYP2A6HTR2ASMN1; SMN2LOXL2
SCHEMBL28667819 0.64 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119191989-A Reduction process of 2, 2-dinitrobibenzyl 浙江华洲药业有限公司 2024-12-27 CN claimed
CN-119191989-A Reduction process of 2, 2-dinitrobibenzyl 浙江华洲药业有限公司 2024-12-27 CN disclosed
CN-107298645-B Method for preparing 2, 2' -dinitrobibenzyl 甘肃皓天医药科技有限责任公司 2020-04-03 CN disclosed
CN-106588774-B A method of catalyzing and synthesizing iminodibenzyl 兰州大学 2019-05-14 CN disclosed
CN-106588774-B A method of catalyzing and synthesizing iminodibenzyl 兰州大学 2019-05-14 CN disclosed
CN-106588774-A Method for catalytic synthesis of iminodibenzyl 兰州大学 2017-04-26 CN disclosed