SCHEMBL734440

SCHEMBL734440

NC1(N)C=CC=CC1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 17/20 0.38
MAOA P21397 16/20 0.38
MAOB P27338 16/20 0.38
HTR2A P28223 2/20 0.34
HTR2C P28335 2/20 0.34
HTR2B P41595 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29806042 0.89
SCHEMBL1153469 0.83 KDM1A (0.44) KDM1AMAOAMAOBHTR2AHTR2C
SCHEMBL9100196 0.82 KDM1A (0.34) KDM1AMAOAMAOBHTR2AHTR2C
SCHEMBL5149443 0.82 HTR2A (0.39) KDM1AMAOAMAOBHTR2AHTR2C
SCHEMBL365626 0.81 CHRNA7 (0.32)
SCHEMBL2870312 0.80 MAOA (0.39) KDM1AMAOAMAOBHTR2AHTR2C
SCHEMBL20839329 0.77 MAOA (0.32) KDM1AMAOAMAOB
SCHEMBL31716197 0.77 CUL4A (0.35) KDM1AMAOAMAOB
SCHEMBL5458200 0.77
SCHEMBL6984232 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115948022-A Prepreg, circuit board and printed circuit board 浙江华正新材料股份有限公司 2023-04-11 CN disclosed
CN-107709424-B Systems and methods for producing aerogel materials 气凝胶科技有限责任公司 2022-08-02 CN disclosed
EP-3029041-B1 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORP (US) 2020-03-04 EP disclosed
US-20200061062-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2020-02-27 US disclosed
US-10398695-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2019-09-03 US disclosed
US-20180360832-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2018-12-20 US disclosed
US-10010550-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2018-07-03 US disclosed
US-20170340633-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2017-11-30 US disclosed
EP-3159737-A1 LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT Nissan Chemical Industries, Ltd. (JP) 2017-04-26 EP disclosed
US-20170049772-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2017-02-23 US disclosed
US-20020161014-A1 Purinyl substituted quinazoline-4-one derivatives ICOS CORPORATION, A DELAWARE CORPORATION 2002-10-31 US disclosed
WO-2001081346-A2 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2001-11-01 WO disclosed
US-5347019-A REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES CASSELLA AG (DE) 1994-09-13 US disclosed
EP-0270665-A4 SOLVENTLESS POLYURETHANE SPRAY COMPOSITIONS AND METHOD FOR APPLYING THEM. AMERON INC (US) 1988-09-28 EP disclosed
EP-0270665-A1 SOLVENTLESS POLYURETHANE SPRAY COMPOSITIONS AND METHOD FOR APPLYING THEM AMERON, INC. (US) 1988-06-15 EP disclosed
WO-1987007287-A1 SOLVENTLESS POLYURETHANE SPRAY COMPOSITIONS AND METHOD FOR APPLYING THEM AMERON, INC. (US) 1987-12-03 WO disclosed
US-4695618-A Solventless polyurethane spray compositions and method for applying them AMERON, INC. (US) 1987-09-22 US disclosed
US-4369318-A USING A BENZO-OR PYRIDO-CINNOLINES AS BLEACH CATALYST CIBA-GEIGY LTD. (CH) 1983-01-18 US disclosed
US-4266011-A FUSED PYRIDAZINE CATALYST CIBA-GEIGY AG (CH) 1981-05-05 US disclosed
US-4008254-A Ceria catalyzed conversion of phenols to dibenzofurans in the presence of water vapor MONSANTO COMPANY (US) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170340633-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG KDM1A 2892/4885MAOA 4472/4885MAOB 4415/4885
US-20180360832-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG KDM1A 2892/4885MAOA 4472/4885MAOB 4415/4885
US-20020161014-A1 Purinyl substituted quinazoline-4-one derivatives PIK3CD, PIK3CA, PIK3CG KDM1A 3109/4885MAOA 3760/4885MAOB 4002/4885
US-20170049772-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG KDM1A 3066/4885MAOA 4624/4885MAOB 4555/4885
US-20200061062-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG KDM1A 2892/4885MAOA 4472/4885MAOB 4415/4885
US-10010550-B2 Inhibitors of human phosphatidylinositol 3-kinase delta PIK3CD, PIK3CA, PIK3CG KDM1A 2892/4885MAOA 4472/4885MAOB 4415/4885
US-10398695-B2 Inhibitors of human phosphatidylinositol 3-kinase delta PIK3CD, PIK3CA, PIK3CG KDM1A 2892/4885MAOA 4472/4885MAOB 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.