Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenyl Dihydrogen Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.79 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.48 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Dihydrogen Phosphate SCHEMBL28144640 | 0.96 | SRC (0.79) | SRCLTA4HNR1H2BAXINPPL1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL6248315 | 0.94 | SRC (0.83) | SRCLTA4HNR1H2BAXINPPL1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL29050735 | 0.92 | SRC (0.79) | SRCLTA4HNR1H2BAXINPPL1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL9501417 | 0.91 | SRC (0.95) | SRCINPPL1INPP5ATDP1L3MBTL1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL28311333 | 0.89 | SRC (1.00) | SRCINPPL1INPP5ATDP1L3MBTL1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL20263 | 0.89 | SRC (1.00) | SRCINPPL1INPP5ATDP1L3MBTL1 | |
| Biphenyl SCHEMBL28533856 | 0.88 | SRC (0.67) | SRCLTA4HNR1H2BAXINPPL1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL23581620 | 0.87 | SRC (0.95) | SRCINPPL1INPP5ATDP1L3MBTL1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL187840 | 0.87 | SRC (0.95) | SRCINPPL1INPP5ATDP1L3MBTL1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL11220366 | 0.87 | SRC (0.95) | SRCINPPL1INPP5ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106604949-A | Alkoxy polycarbonates, bisphenol monomers, and methods of making and using the same | 沙特基础工业全球技术公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106604949-A | Alkoxy polycarbonates, bisphenol monomers, and methods of making and using the same | 沙特基础工业全球技术公司 | 2017-04-26 | — | — | CN | disclosed |