SCHEMBL2814519

SCHEMBL2814519

[CH2]c1c(Cl)c([CH2])c(Cl)c(Cl)c1Cl

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL326581 0.95 MEN1 (0.33) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL2335528 0.91
SCHEMBL6753050 0.86 MEN1 (0.33) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL15352193 0.81
SCHEMBL15352364 0.72
SCHEMBL15054055 0.70 TSHR (0.56) MEN1ALDH1A1LMNAMAPTHPGD
Perchlorobenzene SCHEMBL26562 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD
Perchlorobenzene SCHEMBL8872243 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD
Perchlorobenzene SCHEMBL1330781 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL1547847 0.65 CYP3A4 (0.56) MEN1ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3543267-A1 URETHANE RESIN USING POLYROTAXANE, AND POLISHING PAD Tokuyama Corporation (JP) 2019-09-25 EP disclosed
US-20100240713-A1 AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS XENON PHARMACEUTICALS INC. (CA) 2010-09-23 US disclosed
US-4212996-A USING AN IRON OR ALUMINUM MASKING (COMPLEXING) AGENT CONTAINING AMINOACETIC ACID GROUPS DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
US-4211730-A HALOBROMOBENZYL ACRYLATE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-07-08 US disclosed
US-4128709-A Acrylate-based polymers and their use as flameproofing agents DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240713-A1 AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS SLC40A1, PAH, FECH MEN1 933/4885ALDH1A1 749/4885LMNA 3426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.