Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | CCR4 | P51679 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28293560 | 0.78 | NFE2L2 (0.40) | MEN1KMT2ALRRK2CCR4NFE2L2 | |
| SCHEMBL6028784 | 0.76 | SLC22A12 (0.44) | MEN1KMT2ALRRK2CCR4NFE2L2 | |
| SCHEMBL28421207 | 0.75 | CCR4 (0.32) | CCR4 | |
| SCHEMBL28419440 | 0.75 | PIK3C3 (0.33) | CCR4PIK3C3 | |
| Hydrochloric Acid SCHEMBL28258310 | 0.71 | EGFR (0.36) | HIPK2SMN1; SMN2 | |
| SCHEMBL772591 | 0.71 | ERN1 (0.46) | CSNK2A1HIPK2MEN1KMT2ALRRK2 | |
| SCHEMBL3475483 | 0.71 | HPGD (0.42) | CSNK2A1HIPK2MEN1KMT2ALRRK2 | |
| SCHEMBL23112014 | 0.70 | CSNK2A1 (0.40) | CSNK2A1HIPK2GAAAPAF1TDP2 | |
| SCHEMBL30765070 | 0.70 | CSNK2A1 (0.40) | CSNK2A1HIPK2GAAAPAF1TDP2 | |
| SCHEMBL22090396 | 0.70 | TDP1 (0.42) | CSNK2A1HIPK2MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334527-B | Sulfonamide compounds and uses as tnap inhibitors | 桑福德-伯纳姆医学研究院 | 2017-05-24 | — | — | CN | disclosed |