Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121360 | 0.84 | SLC22A12 (0.44) | SLC22A12NFE2L2CCR4LRRK2HSD11B1 | |
| SCHEMBL31121359 | 0.84 | SLC22A12 (0.44) | SLC22A12NFE2L2CCR4LRRK2HSD11B1 | |
| SCHEMBL4394771 | 0.84 | SLC22A12 (0.44) | SLC22A12NFE2L2CCR4LRRK2HSD11B1 | |
| SCHEMBL28145289 | 0.76 | CSNK2A1 (0.36) | NFE2L2CCR4LRRK2MEN1KMT2A | |
| SCHEMBL24246943 | 0.74 | SLC22A12 (0.44) | SLC22A12NFE2L2LRRK2AHR | |
| Hydrochloric Acid SCHEMBL28293560 | 0.74 | NFE2L2 (0.40) | NFE2L2CCR4LRRK2SCN9AMEN1 | |
| SCHEMBL29488309 | 0.73 | SLC22A12 (0.39) | SLC22A12NFE2L2SCN5ASCN9A | |
| SCHEMBL23012638 | 0.73 | SLC22A12 (0.39) | SLC22A12NFE2L2SCN5ASCN9A | |
| SCHEMBL13415859 | 0.73 | SLC22A12 (0.40) | SLC22A12NFE2L2LRRK2AHR | |
| SCHEMBL9280550 | 0.73 | SLC22A12 (0.40) | SLC22A12NFE2L2LRRK2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732390-A2 | A HERBICIDAL COMBINATION | Syngenta Participations AG (CH) | 2006-12-20 | — | — | EP | claimed |
| WO-2005092101-A2 | A HERBICIDAL COMBINATION | SYNGENTA PARTICIPATIONS AG (CH) | 2005-10-06 | — | — | WO | claimed |
| EP-1732390-A2 | A HERBICIDAL COMBINATION | Syngenta Participations AG (CH) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092101-A2 | A HERBICIDAL COMBINATION | SYNGENTA PARTICIPATIONS AG (CH) | 2005-10-06 | — | — | WO | disclosed |