Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856017 | 0.86 | CHEK1 (0.31) | CHEK1 | |
| SCHEMBL435598 | 0.86 | LIMK1 (0.37) | LIMK1LMNA | |
| SCHEMBL28190077 | 0.81 | MAPT (0.31) | MAPTGAAHTTKDM4ELMNA | |
| SCHEMBL8552177 | 0.77 | LIMK1 (0.34) | LIMK1 | |
| SCHEMBL27099013 | 0.74 | PDPK1 (0.36) | LIMK1MAPTHTTKMT2A | |
| SCHEMBL14386274 | 0.74 | CHEK1 (0.37) | MAPTGAAHTTKDM4ELMNA | |
| SCHEMBL2063119 | 0.74 | HTT (0.34) | MAPTGAAHTTKDM4ELMNA | |
| SCHEMBL6316984 | 0.72 | CHUK (0.32) | LMNA | |
| SCHEMBL678617 | 0.69 | EGFR (0.36) | LIMK1HTTLMNAKMT2ACHEK1 | |
| SCHEMBL11597508 | 0.69 | CYP3A4 (0.41) | MAPTHTTKDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661019-A | Indolizine derivatives as phoshoinositide 3-kinases inhibitors | 奇斯药制品公司 | 2017-05-10 | — | — | CN | disclosed |