SCHEMBL8552177

SCHEMBL8552177

[NH]c1ncnc(N)c1NC=O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435598 0.86 LIMK1 (0.37) LIMK1
SCHEMBL28145458 0.77 LIMK1 (0.33) LIMK1
SCHEMBL27099013 0.74 PDPK1 (0.36) LIMK1
SCHEMBL6309439 0.67 NOS3 (0.33)
Purine SCHEMBL18132338 0.66 PI4KA (0.33)
Purine SCHEMBL18132340 0.65 PI4KA (0.41)
SCHEMBL8856017 0.64 CHEK1 (0.31)
SCHEMBL28190077 0.63 MAPT (0.31)
SCHEMBL8928297 0.63 MEN1 (0.33) LIMK1
SCHEMBL19263989 0.62 PI4KA (0.39) LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719265-B1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT ENERGIE ATOMIQUE (FR) 1998-12-02 EP claimed
EP-0719265-A1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1996-07-03 EP claimed
WO-1995007907-A1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1995-03-23 WO claimed
EP-0719265-A1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1996-07-03 EP disclosed
WO-1995007907-A1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1995-03-23 WO disclosed