Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28145458 | 0.81 | LIMK1 (0.33) | MAPTGAAHTTKDM4ELMNA | |
| SCHEMBL14386274 | 0.71 | CHEK1 (0.37) | MAPTGAAHTTKDM4ELMNA | |
| SCHEMBL2063119 | 0.71 | HTT (0.34) | MAPTGAAHTTKDM4ELMNA | |
| SCHEMBL31677413 | 0.70 | GALR3 (0.36) | HTTLMNASMN1; SMN2 | |
| SCHEMBL2064331 | 0.70 | GALR3 (0.36) | HTTLMNASMN1; SMN2 | |
| SCHEMBL8856017 | 0.70 | CHEK1 (0.31) | — | |
| SCHEMBL435598 | 0.70 | LIMK1 (0.37) | LMNA | |
| SCHEMBL678617 | 0.67 | EGFR (0.36) | HTTLMNAKMT2A | |
| SCHEMBL28847871 | 0.67 | HTT (0.35) | HTTLMNASMN1; SMN2 | |
| SCHEMBL2065254 | 0.67 | GRM5 (0.35) | MAPTGAAHTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104513235-B | Substituted amino-metadiazine compound and its application method and purposes | 广东东阳光药业有限公司 | 2017-12-05 | — | — | CN | disclosed |