Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13130610 | 0.90 | KDM4E (0.34) | IDO1KDM4EGAAMAPTLMNA | |
| SCHEMBL16538494 | 0.80 | IDO1 (0.41) | IDO1SLC6A2SLC6A4LMNAMEN1 | |
| SCHEMBL20301578 | 0.80 | IDO1 (0.35) | IDO1CCKBR | |
| SCHEMBL28094663 | 0.78 | BCHE (0.36) | KDM4EGAAMAPTLMNA | |
| SCHEMBL20321883 | 0.76 | IDO1 (0.39) | IDO1KDM4EGAAMAPTMEN1 | |
| SCHEMBL10984066 | 0.76 | KDM4E (0.36) | KDM4EGAAMAPTLMNAMEN1 | |
| SCHEMBL28842010 | 0.75 | THRA (0.38) | KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL28388284 | 0.75 | THRA (0.38) | KDM4EGAAMAPTLMNAHSD17B10 | |
| SCHEMBL4471183 | 0.75 | CCKBR (0.39) | IDO1CCKBRSLC6A2SLC6A4MEN1 | |
| SCHEMBL6254408 | 0.75 | AOC3 (0.43) | GAASLC6A2SLC6A4AOC3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658643-B | IDO inhibitor | 百时美施贵宝公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-105324362-B | Ido inhibitors | 百时美施贵宝公司 | 2017-05-24 | — | — | CN | disclosed |