Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | MYLK | Q15746 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92545 | 0.91 | KDM4E (0.56) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL5013 | 0.91 | KDM4E (0.52) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL477197 | 0.91 | KDM4E (0.52) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL21040872 | 0.89 | KDM4E (0.54) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL189869 | 0.89 | KDM4E (0.54) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8742086 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL311054 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Potassium SCHEMBL30601760 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Piperazine SCHEMBL28080505 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Methylene Chloride SCHEMBL16447276 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379576-B | Substituted pyrrolidines as factor XIA inhibitors for the treatment of thromboembolic disorders | 小野药品工业株式会社 | 2017-05-10 | — | — | CN | disclosed |