Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886554 | 0.84 | TSHR (0.52) | TSHRNOS1LMNAGAAMAPK1 | |
| SCHEMBL1647740 | 0.83 | MAPK1 (0.55) | MAPTKMT2ATSHRNOS1MAPK1 | |
| SCHEMBL1646651 | 0.83 | TDP1 (0.52) | KMT2ATSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL27030782 | 0.81 | ALDH1A1 (0.53) | MAPTKMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL27932154 | 0.81 | TSHR (0.57) | TSHRNOS1LMNAGAAMAPK1 | |
| SCHEMBL27796885 | 0.81 | ALDH1A1 (0.48) | MAPTKMT2ATSHRLMNAMAPK1 | |
| SCHEMBL1644927 | 0.80 | PTPRC (0.57) | MAPTKMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL5674580 | 0.80 | POLB (0.54) | MAPTTSHRNOS1LMNAGAA | |
| SCHEMBL31303067 | 0.80 | PTPRC (0.57) | MAPTKMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL4800395 | 0.80 | CYP19A1 (0.49) | MAPTKMT2ATSHRNOS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246984-A1 | HETEROCYCLIC JAK INHIBITOR | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2024-07-25 | — | — | US | disclosed |
| EP-4310088-A1 | HETEROCYCLIC JAK INHIBITOR | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2024-01-24 | — | — | EP | disclosed |
| EP-4310088-A1 | HETEROCYCLIC JAK INHIBITOR | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2024-01-24 | — | — | EP | disclosed |
| CN-113614087-B | WEE1 inhibitor and preparation and application thereof | 首药控股(北京)股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-113336760-B | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-11-04 | — | — | CN | disclosed |
| WO-2022127869-A1 | HETEROCYCLIC JAK INHIBITOR | 北京诺诚健华医药科技有限公司 | 2022-06-23 | — | — | WO | disclosed |
| CN-114644633-A | Heterocyclic JAK inhibitors | 北京诺诚健华医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-113620821-A | Preparation method of hordenine hydrochloride | 广汉市派瑞林科技有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-113614087-A | WEE1 inhibitor, and preparation and application thereof | 首药控股(北京)股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113336760-A | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-108349981-B | Novel pyrazolo [3, 4-d ] pyrimidine compound or salt thereof | 大鹏药品工业株式会社 | 2021-03-30 | — | — | CN | disclosed |
| CN-111718348-A | WEE1 inhibitor, and preparation and application thereof | 首药控股(北京)有限公司 | 2020-09-29 | — | — | CN | disclosed |
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2010-09-30 | — | — | US | disclosed |
| CN-101679215-A | New benzamide derivatives as the follicle stimulating hormone conditioning agent | ADDEX PHARMA SA | 2010-03-24 | — | — | CN | disclosed |
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | FSHR, GNRHR, SHBG | MAPT 4813/4885KMT2A 1767/4885TSHR 19/4885 |
| US-20240246984-A1 | HETEROCYCLIC JAK INHIBITOR | JAK2, JAK1, JAK3 | MAPT 3646/4885KMT2A 562/4885TSHR 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.