Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112428 | 0.84 | KDM4E (0.49) | PIN1KDM4ESMN1; SMN2NAMPTALDH1A1 | |
| SCHEMBL23835762 | 0.80 | KDM4E (0.49) | PIN1KDM4ESMN1; SMN2NAMPTALDH1A1 | |
| SCHEMBL24450252 | 0.80 | SMN1; SMN2 (0.52) | KDM4ESMN1; SMN2NAMPTALDH1A1HPSE | |
| SCHEMBL23836090 | 0.77 | KDM5A (0.51) | KDM4ESMN1; SMN2NAMPTALDH1A1HPSE | |
| SCHEMBL25789859 | 0.77 | NAMPT (0.58) | KDM4ESMN1; SMN2NAMPTHPSE | |
| SCHEMBL160155 | 0.76 | AURKA (0.61) | PIN1KDM4ESMN1; SMN2ALDH1A1PKM | |
| SCHEMBL29414293 | 0.76 | AURKA (0.61) | PIN1KDM4ESMN1; SMN2ALDH1A1PKM | |
| SCHEMBL5261395 | 0.75 | KDM4C (0.57) | KDM4E | |
| Water SCHEMBL16239370 | 0.74 | AURKA (0.59) | PIN1KDM4ESMN1; SMN2ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL3808279 | 0.74 | AURKA (0.59) | PIN1KDM4ESMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2831085-A2 | EMM-19: NOVEL ZEOLITIC IMIDAZOLATE FRAMEWORK MATERIAL, METHODS FOR MAKING SAME, AND USES THEREOF | ExxonMobil Research and Engineering Company (US) | 2015-02-04 | — | — | EP | claimed |
| EP-2831086-A2 | LINKER EXCHANGE IN ZEOLITIC IMIDAZOLATE FRAMEWORKS | ExxonMobil Research and Engineering Company (US) | 2015-02-04 | — | — | EP | claimed |
| US-8920541-B2 | Linker exchange in zeolitic imidazolate frameworks | EXXONMOBILE RESEARCH AND ENGINEERING COMPANY (US) | 2014-12-30 | — | — | US | claimed |
| US-8907102-B2 | EMM19 novel zeolitic imidazolate framework material, methods for making same, and uses thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-12-09 | — | — | US | claimed |
| US-8636969-B2 | EMM19star novel zeolitic imidazolate framework material, methods for making same, and uses thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-01-28 | — | — | US | claimed |
| US-20130296568-A1 | EMM19 NOVEL ZEOLITIC IMIDAZOLATE FRAMEWORK MATERIAL, METHODS FOR MAKING SAME, AND USES THEREOF | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2013-11-07 | — | — | US | claimed |
| US-20130259792-A1 | EMM19star NOVEL ZEOLITIC IMIDAZOLATE FRAMEWORK MATERIAL, METHODS FOR MAKING SAME, AND USES THEREOF | EXXONMOBIL RESEARCH & ENGINEERING COMPANY (US) | 2013-10-03 | — | — | US | claimed |
| US-20130259783-A1 | LINKER EXCHANGE IN ZEOLITIC IMIDAZOLATE FRAMEWORKS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-10-03 | — | — | US | claimed |
| WO-2013148975-A2 | EMM-19: NOVEL ZEOLITIC IMIDAZOLATE FRAMEWORK MATERIAL, METHODS FOR MAKING SAME, AND USES THEREOF | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-10-03 | — | — | WO | claimed |
| WO-2013148982-A2 | LINKER EXCHANGE IN ZEOLITIC IMIDAZOLATE FRAMEWORKS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-10-03 | — | — | WO | claimed |
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2010-09-30 | — | — | US | claimed |
| US-10767027-B1 | Magnetically-recoverable catalysts for depolymerization | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2020-09-08 | — | — | US | disclosed |
| EP-2831087-A2 | ZEOLITIC IMIDAZOLATE FRAMEWORK MATERIAL, METHODS FOR MAKING SAME, AND USES THEREOF | ExxonMobil Research and Engineering Company (US) | 2015-02-04 | — | — | EP | disclosed |
| EP-2831086-A2 | LINKER EXCHANGE IN ZEOLITIC IMIDAZOLATE FRAMEWORKS | ExxonMobil Research and Engineering Company (US) | 2015-02-04 | — | — | EP | disclosed |
| EP-2831085-A2 | EMM-19: NOVEL ZEOLITIC IMIDAZOLATE FRAMEWORK MATERIAL, METHODS FOR MAKING SAME, AND USES THEREOF | ExxonMobil Research and Engineering Company (US) | 2015-02-04 | — | — | EP | disclosed |
| WO-2008140788-A1 | ADSORPTIVE GAS SEPARATION OF MULTI-COMPONENT GASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-20 | — | — | WO | disclosed |
| EP-1988996-A2 | PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS | The Regents of the University of Michigan (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |
| WO-2007101241-A2 | PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-09-07 | — | — | WO | disclosed |
| US-20070202038-A1 | PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | FSHR, GNRHR, SHBG | PIN1 3949/4885KDM4E 1395/4885SMN1; SMN2 4686/4885 |
| US-20070202038-A1 | PREPARATION OF FUNCTIONALIZED ZEOLITIC FRAMEWORKS | SOD1, HNRNPF, GTF2F1 | PIN1 1360/4885KDM4E 1297/4885SMN1; SMN2 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.