SCHEMBL28146191

SCHEMBL28146191

O=CC(=O)c1occ(Br)c1Br

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28105938 0.80
SCHEMBL3744691 0.76 CYP1A2 (0.33) ALDH1A1
SCHEMBL27771525 0.67 NQO1 (0.32) ALDH1A1MAPK1TDP1
SCHEMBL28000497 0.66 PTPN1 (0.39) ALDH1A1TDP1
SCHEMBL9013321 0.64
SCHEMBL8620985 0.63 ALDH1A1 (0.41) ALDH1A1MAPK1TDP1
SCHEMBL28064902 0.62 CHRNA4 (0.47) ALDH1A1
SCHEMBL28052202 0.62 PIM1 (0.32) ALDH1A1MAPK1TDP1
SCHEMBL28007109 0.62
SCHEMBL28277344 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106794259-A Method of conjugating peptides or proteins using an agent comprising a leaving group comprising a PEG moiety 宝力泰锐克斯有限公司 2017-05-31 CN disclosed