SCHEMBL8620985

SCHEMBL8620985

O=CC(=O)c1occ2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 4/20 0.35
PTPN1 P18031 3/20 0.35
MEN1 O00255 3/20 0.35
POLB P06746 2/20 0.35
ERN1 O75460 1/20 0.34
MAPT P10636 2/20 0.34
LMNA P02545 1/20 0.34
KDM4E B2RXH2 3/20 0.33
HSD17B10 Q99714 3/20 0.33
HPGD P15428 2/20 0.33
NR4A1 P22736 1/20 0.33
NR4A2 P43354 1/20 0.33
NR4A3 Q92570 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
CYP2C19 P33261 1/20 0.33
PLK1 P53350 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16292878 0.80 KDM4E (0.38) ALDH1A1TDP1KMT2AMEN1KDM4E
SCHEMBL5353695 0.79 KDM4E (0.36) ALDH1A1TDP1KMT2AMEN1MAPT
SCHEMBL547449 0.79 KDM4E (0.45) ALDH1A1TDP1MAPK1KMT2AMEN1
SCHEMBL28811793 0.77 SIRT1 (0.37) ALDH1A1TDP1KMT2AMEN1MAPT
SCHEMBL5309791 0.77 CA12 (0.37) ALDH1A1TDP1KMT2AMEN1MAPT
SCHEMBL826674 0.77 KDM4E (0.35) ALDH1A1TDP1KMT2AMEN1MAPT
SCHEMBL9565260 0.77 KDM4E (0.35) ALDH1A1TDP1KMT2AMEN1KDM4E
SCHEMBL3383913 0.77 KDM4E (0.35) ALDH1A1TDP1KMT2AMEN1KDM4E
Hydrochloric Acid SCHEMBL11395268 0.77 LDHA (0.44) ALDH1A1TDP1MAPK1KMT2AMEN1
SCHEMBL649403 0.77 ALDH1A1 (0.41) ALDH1A1TDP1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106257977-B Composite polyamide membrane post-treated with nitrous acid DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-29 CN claimed
CN-107674205-A Thermosetting wholly aromatic polyester imide liquid crystal and preparation method thereof 苏州大学 2018-02-09 CN claimed
CN-107667152-A Coating composition 株式会社KCC 2018-02-06 CN claimed
CN-106257977-A Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2016-12-28 CN claimed
CN-104245685-B The production method of (acetylene-1,2-diyl) double (isobenzofuran-1,3-diketone) 聂克斯姆化学有限公司 2016-09-07 CN claimed
CN-103168023-B Linking agent NEXAM CHEMICAL AB (SE) 2016-01-06 CN claimed
CN-103429636-B Compositions for improving polyesters NEXAM CHEMICAL AB 2015-06-24 CN claimed
CN-104725602-A Easily processed dianhydride hardener for epoxy resin systems based on 5,5 '-oxybis (isobenzofuran-1,3-dion) EVONIK INDUSTRIES AG 2015-06-24 CN claimed
CN-104725601-A Easily processed dianhydride hardener for epoxy resin systems based on 5,5 '-dicarbonyl (isobenzofuran-1,3-dion) EVONIK INDUSTRIES AG 2015-06-24 CN claimed
CN-102844291-B Novel crosslinking agent NEXAM CHEMICAL AB 2015-06-17 CN claimed
CN-103619912-A Improved oligo- and polyimide NEXAM CHEMICAL AB 2014-03-05 CN claimed
CN-103524715-A Hardener for epoxy resin systems and their applications EVONIK INDUSTRIES AG 2014-01-22 CN claimed
CN-103429636-A Compositions for improving polyesters NEXAM CHEMICAL AB 2013-12-04 CN claimed
CN-101663309-B Process for preparing substituted pentacenes MERCK PATENT GMBH 2013-08-14 CN claimed
CN-103168023-A Cross-linkable agent NEXAM CHEMICAL AB 2013-06-19 CN claimed
CN-102892800-A Crosslinking catalysis NEXAM CHEMICAL A 2013-01-23 CN claimed
CN-102844291-A Novel crosslinking agent NEXAM CHEMICAL AB 2012-12-26 CN claimed
CN-101663309-A Process for preparing substituted pentacenes MERCK PATENT GMBH 2010-03-03 CN claimed
CN-1449418-A No-flow fluxing adhesive composition 3M INNOVATIVE PROPERTIES CO (US) 2003-10-15 CN claimed
US-4613611-A HYPOGLYCEMIC AGENTS AMERICAN CYANAMID COMPANY (US) 1986-09-23 US claimed