Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.71 |
| ▸ | NPC1 | O15118 | 8/20 | 0.71 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | DHODH | Q02127 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | ACP1 | P24666 | 1/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834924 | 0.85 | RAB9A (0.72) | RAB9ANPC1CD274MEN1KMT2A | |
| SCHEMBL27815206 | 0.83 | RAB9A (0.81) | RAB9ANPC1CD274MEN1KMT2A | |
| SCHEMBL27834920 | 0.82 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AAPP | |
| SCHEMBL13457180 | 0.81 | ROCK2 (0.70) | RAB9ANPC1CD274 | |
| SCHEMBL1913680 | 0.80 | NPC1 (0.71) | RAB9ANPC1MEN1KMT2ACSNK1D | |
| SCHEMBL28844162 | 0.80 | NPC1 (0.60) | RAB9ANPC1MEN1KMT2AAPP | |
| SCHEMBL28147052 | 0.80 | CSNK1D (0.64) | RAB9ANPC1MEN1KMT2AAPP | |
| SCHEMBL3463497 | 0.78 | NPC1 (0.81) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5027241 | 0.77 | RAB9A (0.80) | RAB9ANPC1MEN1KMT2ADHODH | |
| SCHEMBL27681825 | 0.77 | MAPT (0.57) | RAB9ANPC1MEN1KMT2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565631-B | A kind of method that heteroaryl amine reacts synthesis substitution heteroaryl amine with amine | 温州大学 | 2018-11-30 | — | — | CN | disclosed |
| CN-106565631-A | Method for synthesizing substituent miscellaneous aromatic amine through reaction between miscellaneous aromatic amine and amine | 温州大学 | 2017-04-19 | — | — | CN | disclosed |