Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.67 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.67 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035846 | 0.86 | NR1H2 (0.71) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL14521015 | 0.86 | NR1H2 (0.71) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL26464405 | 0.84 | NPC1 (0.67) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL11319935 | 0.82 | NR1H2 (0.73) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL17280061 | 0.81 | NPC1 (0.55) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL1260404 | 0.81 | KIF11 (0.58) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL1230235 | 0.81 | NPC1 (0.50) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL28147211 | 0.80 | NR1H2 (1.00) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL27935074 | 0.80 | NPC1 (0.49) | NR1H2NR1H3DGAT1NPC1RAB9A | |
| SCHEMBL15299217 | 0.77 | AOC3 (0.52) | NR1H2NR1H3DGAT1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632106-A | Synthetic method of asymmetric 1,2,4-triazole derivatives | 安徽师范大学 | 2017-05-10 | — | — | CN | disclosed |