Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.50 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521015 | 0.86 | NR1H2 (0.71) | NPC1RAB9ALMNAKIF11KDM4E | |
| SCHEMBL29035846 | 0.86 | NR1H2 (0.71) | NPC1RAB9ALMNAKIF11KDM4E | |
| SCHEMBL28147205 | 0.84 | NR1H2 (0.67) | NPC1RAB9ALMNAKDM4EPOLB | |
| SCHEMBL11310455 | 0.82 | NPC1 (0.73) | NPC1RAB9ALMNAKDM4ENR1H2 | |
| SCHEMBL17280061 | 0.81 | NPC1 (0.55) | NPC1RAB9ALMNAKDM4EPOLB | |
| SCHEMBL1230235 | 0.81 | NPC1 (0.50) | NPC1RAB9ALMNAKIF11KDM4E | |
| SCHEMBL1260404 | 0.81 | KIF11 (0.58) | NPC1RAB9ALMNAKIF11KDM4E | |
| SCHEMBL26101505 | 0.81 | NPC1 (0.61) | NPC1RAB9ALMNAKDM4EPOLB | |
| SCHEMBL8726592 | 0.80 | ALPL (0.61) | NPC1RAB9ALMNAKIF11KDM4E | |
| SCHEMBL27935074 | 0.80 | NPC1 (0.49) | NPC1RAB9ALMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |
| EP-4173485-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-03 | — | — | EP | disclosed |