Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168101 | 1.00 | BACE1 (0.37) | BACE1PTK2CYP3A4APPBACE2 | |
| SCHEMBL3924687 | 0.82 | MKNK1 (0.42) | BACE1CYP3A4PLAUSLC9A1LMNA | |
| SCHEMBL5195760 | 0.82 | CYP3A4 (0.46) | BACE1CYP3A4APPBACE2PLAU | |
| Hydrochloric Acid SCHEMBL3171726 | 0.81 | CYP3A4 (0.44) | BACE1CYP3A4APPBACE2PLAU | |
| SCHEMBL4772221 | 0.80 | ABL1 (0.51) | ABL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL19172612 | 0.80 | CFTR (0.43) | BACE1APPBACE2ABL1PLAU | |
| SCHEMBL7692886 | 0.80 | LMNA (0.42) | PTK2POLBALDH1A1MAPTPLAU | |
| Hydrochloric Acid SCHEMBL15226982 | 0.79 | CYP3A4 (0.43) | CYP3A4ALDH1A1MAPTPLAUKMT2A | |
| SCHEMBL18864859 | 0.78 | SPR (0.47) | PTK2CYP3A4POLBKMT2AHCAR2 | |
| SCHEMBL17805386 | 0.78 | POLB (0.39) | BACE1PTK2BACE2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632017-A | Synthetic method of 2-acetamido-5-chloropyridine | 山东友帮生化科技有限公司 | 2017-05-10 | — | — | CN | disclosed |