SCHEMBL28148149

SCHEMBL28148149

Cln1c(-c2ccccc2)cc2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.62
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 3/20 0.49
HPGD P15428 3/20 0.49
KDM4E B2RXH2 2/20 0.49
HSD17B10 Q99714 1/20 0.49
HAO1 Q9UJM8 1/20 0.43
PDGFRB P09619 1/20 0.42
KDR P35968 1/20 0.42
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
ACLY P53396 1/20 0.40
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
BACE1 P56817 3/20 0.39
APP P05067 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28268761 0.77 KMT2A (0.60) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL29581156 0.77 KMT2A (1.00) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL22022081 0.77 KMT2A (0.60) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL28148155 0.77 KMT2A (0.60) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL3285152 0.77 KMT2A (0.60) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL23791207 0.77 KMT2A (0.60) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL214075 0.77 KMT2A (1.00) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL1753892 0.75 KMT2A (0.58) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL13425022 0.75 HAO1 (0.62) KMT2AL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL1878805 0.75 HAO1 (0.58) KMT2AL3MBTL1ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113201526-B Difunctional photo-enzyme synergistic catalyst and preparation method and application thereof 东南大学 2024-04-09 CN claimed
CN-113201526-A Bifunctional photo-enzyme synergistic catalyst and preparation method and application thereof 东南大学 2021-08-03 CN claimed
CN-109053715-A A kind of copper catalysis series connection cyclization constructs N- thiazoline indoles 山东博苑医药化学有限公司 2018-12-21 CN claimed
CN-113201526-B Difunctional photo-enzyme synergistic catalyst and preparation method and application thereof 东南大学 2024-04-09 CN disclosed
CN-113201526-A Bifunctional photo-enzyme synergistic catalyst and preparation method and application thereof 东南大学 2021-08-03 CN disclosed
CN-109665984-A Synthetic method of 2-substituted indole compound 南京工业大学 2019-04-23 CN disclosed
CN-109053715-A A kind of copper catalysis series connection cyclization constructs N- thiazoline indoles 山东博苑医药化学有限公司 2018-12-21 CN disclosed
CN-104736541-B Novel compound and organic electroluminescent element comprising same 株式会社斗山 2017-05-31 CN disclosed