Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656503 | 0.80 | KMT2A (0.43) | KMT2AL3MBTL1ALDH1A1KDM4EACLY | |
| SCHEMBL28148149 | 0.77 | KMT2A (0.62) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL29581156 | 0.75 | KMT2A (1.00) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL3285152 | 0.75 | KMT2A (0.60) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL22022081 | 0.75 | KMT2A (0.60) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL23791207 | 0.75 | KMT2A (0.60) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL214075 | 0.75 | KMT2A (1.00) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL28268761 | 0.75 | KMT2A (0.60) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL1753892 | 0.73 | KMT2A (0.58) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL1878805 | 0.73 | HAO1 (0.58) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053715-A | A kind of copper catalysis series connection cyclization constructs N- thiazoline indoles | 山东博苑医药化学有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-109053715-A | A kind of copper catalysis series connection cyclization constructs N- thiazoline indoles | 山东博苑医药化学有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-104703989-B | New compound and the organic electroluminescent device comprising it | 株式会社斗山 | 2017-09-29 | — | — | CN | disclosed |
| CN-104736541-B | Novel compound and organic electroluminescent element comprising same | 株式会社斗山 | 2017-05-31 | — | — | CN | disclosed |