Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148728 | 0.89 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL28149888 | 0.87 | CYP19A1 (0.51) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL19742865 | 0.83 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL21500640 | 0.81 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL28149889 | 0.80 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL28140205 | 0.80 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL28148749 | 0.79 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL28377018 | 0.78 | CYP19A1 (0.61) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL28148737 | 0.78 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL28148755 | 0.78 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384668-B | compounds and compositions for inhibition of NAMPT | 福马TM有限责任公司 | 2017-05-31 | — | — | CN | claimed |