Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28149888 | 0.90 | CYP19A1 (0.51) | CYP11B1CYP11B2HTR1AHTR2CCYP19A1 | |
| SCHEMBL28148728 | 0.89 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL28148752 | 0.80 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL19742865 | 0.80 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL21500662 | 0.79 | NAMPT (0.49) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL22399266 | 0.76 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL164101 | 0.76 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL28148737 | 0.75 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL159804 | 0.75 | CYP11B1 (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL173715 | 0.75 | NAMPT (0.54) | CYP11B1CYP11B2CYP19A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384668-B | compounds and compositions for inhibition of NAMPT | 福马TM有限责任公司 | 2017-05-31 | — | — | CN | claimed |