SCHEMBL19742865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28148737	0.89	CYP11B1 (0.60)	CYP11B1CYP19A1CYP11B2CYP1A2POLB
	SCHEMBL28148752	0.83	CYP11B1 (0.54)	CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6
	SCHEMBL21500640	0.83	CYP11B1 (0.55)	CYP11B1CYP19A1CYP11B2TBXAS1CYP2A6
	SCHEMBL28377018	0.83	CYP19A1 (0.61)	CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6
	SCHEMBL22399266	0.82	CYP11B1 (0.51)	CYP11B1CYP19A1CYP11B2CYP1A2POLB
	SCHEMBL21500662	0.82	NAMPT (0.49)	CYP11B1CYP19A1CYP11B2CYP1A2POLB
	SCHEMBL22063900	0.82	CYP11B1 (1.00)	CYP11B1CYP19A1CYP11B2CYP1A2POLB
	Benzylimidazole SCHEMBL414	0.82	CYP11B1 (1.00)	CYP11B1CYP19A1CYP11B2CYP1A2POLB
	SCHEMBL28149990	0.82	POLB (0.54)	CYP11B1CYP19A1CYP11B2CYP1A2POLB
	SCHEMBL164101	0.81	CYP11B1 (0.47)	CYP11B1CYP19A1CYP11B2CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.