Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30167783 | 1.00 | NAMPT (0.44) | NAMPTCYP2C9CYP2D6CYP2C19CA12 | |
| SCHEMBL28148792 | 0.85 | HTR6 (0.41) | NAMPTCYP2C9CYP2D6CYP2C19TYMS | |
| SCHEMBL28148791 | 0.84 | NAMPT (0.46) | NAMPTUSP2TSHR | |
| SCHEMBL30167576 | 0.84 | NAMPT (0.46) | NAMPTUSP2TSHR | |
| SCHEMBL30167580 | 0.78 | NAMPT (0.40) | NAMPTTYMSUSP2TSHR | |
| SCHEMBL28844956 | 0.78 | NAMPT (0.40) | NAMPTTYMSUSP2TSHR | |
| SCHEMBL30167572 | 0.75 | NAMPT (0.43) | NAMPTCYP2C9CYP2D6CYP2C19CA12 | |
| SCHEMBL28203325 | 0.73 | CACNA1I (0.34) | CYP2C9CYP2D6USP2TP53CYP3A4 | |
| SCHEMBL28149958 | 0.69 | TYMS (0.41) | NAMPTCYP2C9CYP2D6CYP2C19TYMS | |
| SCHEMBL27540773 | 0.69 | EPHX2 (0.41) | CYP2C9CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384668-B | compounds and compositions for inhibition of NAMPT | 福马TM有限责任公司 | 2017-05-31 | — | — | CN | claimed |