Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KAT7 | O95251 | 2/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 11/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28150075 | 0.89 | CA12 (0.49) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL28844823 | 0.86 | CA12 (0.58) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL22446082 | 0.83 | CA12 (0.52) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL28150066 | 0.82 | CA12 (0.49) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL28953341 | 0.81 | CA12 (0.50) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL28845079 | 0.80 | CA12 (0.49) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL28844960 | 0.80 | MEN1 (0.43) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL28149998 | 0.80 | CA12 (0.51) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL28149935 | 0.79 | CA12 (0.50) | CA12CA1CA2CA9KAT7 | |
| SCHEMBL28149987 | 0.79 | CA12 (0.50) | CA12CA1CA2CA9KAT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384668-B | compounds and compositions for inhibition of NAMPT | 福马TM有限责任公司 | 2017-05-31 | — | — | CN | claimed |