Urea

Urea

SCHEMBL28149082

CCCS(=O)(=O)O.NC(N)=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
BLM P54132 3/20 0.46
CYP2C19 P33261 2/20 0.46
SLC6A6 P31641 1/20 0.46
APP P05067 1/20 0.42
PTGS1 P23219 1/20 0.39
PDE4A P27815 1/20 0.39
ENPEP Q07075 4/20 0.36
EPHX2 P34913 1/20 0.35
ALDH1A1 P00352 1/20 0.33
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
S1PR2 O95136 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
ALOX15 P16050 1/20 0.32
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL6742297 0.92 LMNA (0.43) LMNABLMCYP2C19SLC6A6APP
Methylamine SCHEMBL28108487 0.88
SCHEMBL28849565 0.88 LMNA (0.47) LMNABLMCYP2C19SLC6A6APP
SCHEMBL5268 0.88
Thiourea SCHEMBL27972110 0.86 LMNA (0.43) LMNABLMCYP2C19SLC6A6APP
Ethylamine SCHEMBL27427305 0.86 LMNA (0.55) LMNABLMCYP2C19SLC6A6APP
SCHEMBL3376538 0.86
SCHEMBL3381686 0.86
Ethane SCHEMBL25228294 0.85
SCHEMBL21859089 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109112509-A A kind of high corrosion-resistant chemical nickel-plating liquid and preparation method thereof 重庆立道新材料科技有限公司 2019-01-01 CN claimed
CN-105862090-B Cyanide-free sulfite gold plating solution and application thereof 深圳市联合蓝海科技开发有限公司 2017-05-03 CN disclosed