Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL28149082 | 0.92 | LMNA (0.46) | LMNABLMSLC6A6CYP2C19ALOX15 | |
| Thioacetamide SCHEMBL6704934 | 0.87 | LMNA (0.42) | LMNABLMSLC6A6CYP2C19APP | |
| SCHEMBL193449 | 0.86 | TDP1 (0.52) | LMNABLMSLC6A6CYP2C19APP | |
| Methylamine SCHEMBL28108487 | 0.86 | — | — | |
| Acetamide SCHEMBL30416363 | 0.86 | BLM (0.50) | LMNABLMSLC6A6CYP2C19ALOX15 | |
| SCHEMBL28849565 | 0.86 | LMNA (0.47) | LMNABLMSLC6A6CYP2C19APP | |
| SCHEMBL5268 | 0.86 | — | — | |
| Thiourea SCHEMBL27972110 | 0.84 | LMNA (0.43) | LMNABLMSLC6A6CYP2C19APP | |
| SCHEMBL3381686 | 0.83 | — | — | |
| SCHEMBL3376538 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428755-A | Process for producing novel nitrogen-containing compound or salt thereof, and intermediate for producing the same | 富士胶片株式会社 | 2017-12-01 | — | — | CN | disclosed |
| US-6689816-B2 | SYNERGISTIC MIXTURE; THERAPY FOR PSYCHOLOGICAL DISORDERS | SYNCHRONEURON | 2004-02-10 | — | — | US | disclosed |
| US-20020119912-A1 | Treatment of posttraumatic strees disorder, obsessive-compulsive disorder and related neuropsychiatric disorders | SYNCHRONEURON INC. | 2002-08-29 | — | — | US | disclosed |
| US-6391922-B1 | ADMINISTERING NEUROTRANSMITTER | SYNCHRONEURON, LLC | 2002-05-21 | — | — | US | disclosed |
| EP-1162960-A2 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF POSTTRAUMATIC STRESS DISORDER | Synchroneuron, LLC (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056301-A2 | TREATMENT OF POSTTRAUMATIC STRESS DISORDER, OBSESSIVE-COMPULSIVE DISORDER AND RELATED NEUROPSYCHIATRIC DISORDERS | SYNCHRONEURON, LLC (US) | 2000-09-28 | — | — | WO | disclosed |