Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28149233 | 0.88 | KMT2A (0.39) | SNCAPDE3BPDE3AKMT2ALMNA | |
| SCHEMBL15534930 | 0.81 | ALDH1A1 (0.43) | SNCALMNAMAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL15535373 | 0.80 | SNCA (0.41) | SNCAPDE3BPDE3AKMT2ALMNA | |
| SCHEMBL15535136 | 0.80 | PDE3B (0.45) | SNCAPDE3BPDE3AKMT2APOLB | |
| SCHEMBL15535010 | 0.80 | SNCA (0.43) | SNCAKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL15535458 | 0.80 | RXRA (0.43) | SNCAPOLBLMNAFFAR1MAPT | |
| SCHEMBL15535465 | 0.80 | AR (0.42) | SNCAKMT2ALMNAMEN1 | |
| SCHEMBL15536028 | 0.79 | ACACB (0.38) | SNCAKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL15535245 | 0.79 | SNCA (0.42) | SNCAPDE3BPDE3AKMT2AMAPT | |
| SCHEMBL15536612 | 0.79 | FFAR1 (0.45) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334525-B | catechol O-methyltransferase activity inhibiting compounds | 奥赖恩公司 | 2017-05-10 | — | — | CN | disclosed |