Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.54 |
| ▸ | RXRB | P28702 | 3/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371525 | 0.88 | ANPEP (0.58) | RXRARXRBANPEPENPEPMRGPRX4 | |
| SCHEMBL30354039 | 0.88 | ANPEP (0.58) | RXRARXRBANPEPENPEPMRGPRX4 | |
| Isophthalic Acid SCHEMBL25190289 | 0.86 | ANPEP (0.56) | RXRARXRBANPEPENPEPMAPT | |
| SCHEMBL28901713 | 0.84 | PTGS1 (0.54) | RXRARXRBANPEPENPEPMAPT | |
| SCHEMBL28149384 | 0.83 | TSHR (0.53) | RXRARXRBANPEPENPEPMRGPRX4 | |
| SCHEMBL6387730 | 0.81 | RXRA (0.55) | RXRARXRBANPEPENPEPMRGPRX4 | |
| SCHEMBL105264 | 0.77 | RXRA (0.66) | RXRARXRBANPEPENPEPMRGPRX4 | |
| SCHEMBL30444032 | 0.77 | RXRA (0.66) | RXRARXRBANPEPENPEPMRGPRX4 | |
| SCHEMBL17069291 | 0.77 | IDO1 (0.50) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17069289 | 0.77 | IDO1 (0.50) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610142-B | 3-bishydrazide diphenylurea derivative, and preparation method and application of 3-bishydrazide diphenylurea derivative | 青岛农业大学 | 2017-05-10 | — | — | CN | disclosed |