SCHEMBL28149384

SCHEMBL28149384

CC(c1cccc(C(=O)O)c1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
CBS P35520 1/20 0.52
KMO O15229 2/20 0.51
ANPEP P15144 1/20 0.46
ENPEP Q07075 1/20 0.46
MRGPRX4 Q96LA9 2/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SRD5A2 P31213 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 2/20 0.43
PTGS1 P23219 2/20 0.43
CXCR1 P25024 2/20 0.43
CXCR2 P25025 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL371525 0.87 ANPEP (0.58) KMOANPEPENPEPMRGPRX4CYP1A2
SCHEMBL30354039 0.87 ANPEP (0.58) KMOANPEPENPEPMRGPRX4CYP1A2
Isophthalic Acid SCHEMBL25190289 0.85 ANPEP (0.56) KMOANPEPENPEPCYP1A2CYP2C9
SCHEMBL6387730 0.83 RXRA (0.55) TSHRANPEPENPEPMRGPRX4SMN1; SMN2
SCHEMBL28901713 0.83 PTGS1 (0.54) TSHRKMOANPEPENPEPSMN1; SMN2
SCHEMBL28149378 0.83 RXRA (0.54) ANPEPENPEPMRGPRX4MEN1KMT2A
SCHEMBL12204112 0.79 IDO1 (0.53) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL10455036 0.77 RXRA (0.68) TSHRANPEPENPEPMRGPRX4CYP2C9
SCHEMBL105264 0.76 RXRA (0.66) KMOANPEPENPEPMRGPRX4CYP1A2
SCHEMBL30444032 0.76 RXRA (0.66) KMOANPEPENPEPMRGPRX4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104610142-B 3-bishydrazide diphenylurea derivative, and preparation method and application of 3-bishydrazide diphenylurea derivative 青岛农业大学 2017-05-10 CN disclosed