Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30883191 | 0.88 | L3MBTL1 (0.43) | NPSR1ALDH1A1PTGIRKCNN4NPC1 | |
| SCHEMBL27499242 | 0.86 | ALB (0.43) | NPSR1ALDH1A1PTGIRKCNN4NPC1 | |
| SCHEMBL6037488 | 0.86 | KDR (0.46) | NPSR1KCNN4NPC1POLBRAB9A | |
| SCHEMBL2098348 | 0.85 | NPSR1 (0.56) | NPSR1ALDH1A1PTGIRNPC1POLB | |
| SCHEMBL5275049 | 0.85 | AKR1B1 (0.44) | NPSR1PTGIRPOLBHTTKDM4E | |
| SCHEMBL2098346 | 0.83 | NPSR1 (0.54) | NPSR1ALDH1A1PTGIRKCNN4NPC1 | |
| SCHEMBL12272679 | 0.81 | L3MBTL1 (0.52) | NPSR1ALDH1A1PTGIRNPC1POLB | |
| SCHEMBL1118587 | 0.81 | NPSR1 (0.52) | NPSR1ALDH1A1PTGIRKCNN4NPC1 | |
| SCHEMBL5271205 | 0.81 | KCNA5 (0.36) | NPSR1ALDH1A1PTGIRKCNN4NPC1 | |
| SCHEMBL75885 | 0.80 | NPSR1 (0.64) | NPSR1ALDH1A1NPC1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610142-B | 3-bishydrazide diphenylurea derivative, and preparation method and application of 3-bishydrazide diphenylurea derivative | 青岛农业大学 | 2017-05-10 | — | — | CN | disclosed |