SCHEMBL30883191

SCHEMBL30883191

NC(=O)N(c1ccccc1F)c1ccccc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
KCNN4 O15554 5/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PARP10 Q53GL7 1/20 0.37
GAA P10253 2/20 0.36
KCNE1 P15382 1/20 0.35
KCNQ1 P51787 1/20 0.35
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
PRKD3 O94806 1/20 0.35
CLK2 P49760 1/20 0.35
DYRK1A Q13627 1/20 0.35
PRKD2 Q9BZL6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28149385 0.88 NPSR1 (0.52) L3MBTL1CES2CES1KCNN4ALDH1A1
SCHEMBL6037488 0.82 KDR (0.46) L3MBTL1KCNN4NPSR1NPC1RAB9A
SCHEMBL3542145 0.81 CES2 (0.40) L3MBTL1CES2CES1KCNN4ALDH1A1
SCHEMBL14053250 0.79 CES2 (0.39) L3MBTL1CES2CES1KCNN4ALDH1A1
SCHEMBL5490028 0.79 DDB1 (0.46) L3MBTL1CES2CES1KCNN4ALDH1A1
SCHEMBL22917055 0.78 L3MBTL1 (0.58) L3MBTL1CES2CES1ALDH1A1ALOX15
SCHEMBL15228984 0.78 L3MBTL1 (0.36) L3MBTL1CES2CES1KCNN4ALDH1A1
SCHEMBL27947466 0.78 ALDH1A1 (0.50) L3MBTL1CES2CES1KCNN4ALDH1A1
SCHEMBL5275049 0.78 AKR1B1 (0.44) NPSR1GAAPTGIR
SCHEMBL5271205 0.78 KCNA5 (0.36) L3MBTL1KCNN4ALDH1A1NPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736059-A Green preparation method of N, N-disubstituted urea and derivative 宁夏大学 2024-03-22 CN disclosed